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FLASH GENE
Symbol NDUFB5 contributors: npt/mct - updated : 11-02-2010
HGNC name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
HGNC id 7700
Location 3q26.33      Physical location : 179.322.574 - 179.342.287
Synonym name
  • NADH-ubiquinone oxidoreductase SGDH subunit
  • complex I-SGDH
  • Synonym symbol(s) SGDH, CI-SGDH, MGC12314, DKFZp686N02262, FLJ30597, MGC111204
    EC.number 1.6.5.3, 1.6.99.3
    DNA
    TYPE functioning gene
    STRUCTURE 19.71 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 1088 - 189 - Loeffen (1998)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • mitochondria transit peptide
  • NADH-ubiquinone oxidoreductase SGDH subunit
  • mono polymer heteromer , complex
    isoforms Precursor
    HOMOLOGY
    interspecies ortholog to murine Ndufb5
    homolog to C.elegans Y17D7A.1
    Homologene
    FAMILY
  • complex I NDUFB5 subunit family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • transfer of electrons from NADH to the respiratory chain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic
    signaling
    a component
  • one of the forty-one subunits of the complex I of respiratory chain
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS