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FLASH GENE

Symbol

NCOA5

contributors: npt - updated : 08-06-2005

HGNC name	nuclear receptor coactivator 5
HGNC id	15909

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	20q12-q13.2      Physical location : 44.689.626 - 44.718.580
Synonym name	coactivator independent of AF-2
Synonym symbol(s)	KIAA1637, CIA, bA465L10.6, NCoA-5

DNA

TYPE	functioning gene
STRUCTURE	29.00 kb     8 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NCOA5 8 - 3209 65.5 579 - -

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a bifunction nuclear receptor interacting domain containing overlapping LXXLL and PhixxPhi, PhiI motif

HOMOLOGY

Homologene

FAMILY

CATEGORY

transcription factor , receptor nuclear

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION

coregulator for estrogen alpha and beta receptors, independent of the AF2 domain of the receptors

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

hormonal

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS