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FLASH GENE
Symbol NCOA5 contributors: npt - updated : 08-06-2005
HGNC name nuclear receptor coactivator 5
HGNC id 15909
Location 20q12-q13.2      Physical location : 44.689.626 - 44.718.580
Synonym name coactivator independent of AF-2
Synonym symbol(s) KIAA1637, CIA, bA465L10.6, NCoA-5
DNA
TYPE functioning gene
STRUCTURE 29.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
RPS2L1 20q13.11 ribosomal protein S2-like 1 WFDC11 20q12-q13.1 WAP four-disulfide core domain 11 WFDC10B 20 WAP four-disulfide core domain 10B WFDC13 20q13.12 WAP four-disulfide core domain 13 LOC391253 20 similar to dJ601O1.1 (novel protein with Kunitz/Bovine pancreatic trypsin inhibitor domain) HNRPA1P3 20q13.12 heterogeneous nuclear ribonucleoprotein A1 pseudogene 3 WFDC3 20q13.12 WAP four-disulfide core domain 3 DNTTIP1 20q13.12 deoxynucleotidyltransferase, terminal, interacting protein 1 UBE2C 20q12-q13.1 ubiquitin-conjugating enzyme E2C TNNC2 20q12-q13.11 troponin C2, fast C20orf161 20q13.11 chromosome 20 open reading frame 161 PTE1 20q12-q13.1 peroxisomal acyl-CoA thioesterase ZSWIM3 20q13.12 zinc finger, SWIM domain containing 3 ZSWIM1 20q13.12 zinc finger, SWIM domain containing 1 C20orf165 20q13.12 chromosome 20 open reading frame 165 C20orf163 20q13.12 chromosome 20 open reading frame 163 PPGB 20q13.1 protective protein for beta-galactosidase (galactosialidosis) PLTP 20q12 phospholipid transfer protein C20orf67 20q13.12 chromosome 20 open reading frame 67 ZNF335 20q11.21-q13.12 zinc finger protein 335 FTLP 20q13.12 ferritin, light polypeptide pseudogene MMP9 20q11.2 matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) LOC128499 20q13.12 hypothetical LOC128499 SLC12A5 20q12-q13.1 solute carrier family 12, (potassium-chloride transporter) member 5 NCOA5 20q12-q13.2 nuclear receptor coactivator 5 RPL13P2 20q13.12 ribosomal protein L13 pseudogene 2 TNFRSF5 20q12-q13.2 tumor necrosis factor receptor superfamily, member 5 CDH22 20q12-q13.1 cadherin-like 22
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 3209 65.5 579 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a bifunction nuclear receptor interacting domain containing overlapping LXXLL and PhixxPhi, PhiI motif
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transcription factor , receptor nuclear
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • coregulator for estrogen alpha and beta receptors, independent of the AF2 domain of the receptors
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS