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FLASH GENE
Symbol NCAPH2 contributors: mct - updated : 25-06-2019
HGNC name non-SMC condensin II complex, subunit H2
HGNC id 25071
Location 22q13.33      Physical location : 50.946.644 - 50.963.208
Synonym name
  • CAP-H2 subunit of the condensin II complex
  • kleisin beta
  • Synonym symbol(s) 384D8-2, 384D8_6, CAP-H2, MGC15858, MGC18000
    DNA
    TYPE functioning gene
    STRUCTURE 15.00 kb     9 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1440 - 299 - Ono
    - - 2070 - 605 - Ono
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousnerve   highly
    Skin/Tegumentskin   highly
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • package chromosomes and hold replicated sister chromatids together between the S and M phases of the cell cycle
  • may be playing in T cell differentiation
  • have important roles in chromosome condensation during mitosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with structural maintenance of chromosomes proteins through N- and C-terminal domains to form a ring-like structure
  • Condensin II subunits, NCAPD3 and NCAPH2, interact with members of the Gamma-Interferon Activated Inhibitor of Translation (GAIT) complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS