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FLASH GENE
Symbol NCAM2 contributors: npt/ - updated : 03-10-2005
HGNC name neural cell adhesion molecule 2
HGNC id 7657
Location 21q21.1      Physical location : 22.370.632 - 22.911.214
Synonym name neural cell adhesion molecule 2 precursor
Synonym symbol(s) NCAM21, MGC51008
DNA
TYPE functioning gene
STRUCTURE 540.58 kb     18 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - D21S18 - D21S1256 - D21S1914 - NCAM2 - D21S265 - D21S1435 - D21S1442 - qter
Authors Paoloni-Giacobino (97)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
18 - 3699 91 837 - Paoloni-Giacobino (1997)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five immunoglobulin-like (Ig) extracellular domains
  • two fibronectin type III-like domains
  • HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • could have a role in the molecular mechanism of homophilic binding (Rasmussen 2008)
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS