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FLASH GENE
Symbol NAXD contributors: mct - updated : 17-11-2016
HGNC name NAD(P)HX dehydratase
HGNC id 25576
Location 13q34      Physical location : -
Synonym name
  • carbohydrate kinase domain
  • Synonym symbol(s) CARKD, LP3298
    EC.number 4.2.1.93
    DNA
    TYPE functioning gene
    STRUCTURE 24.54 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 2617 - 329 - 2014 24611804
    7 - 2331 - 237 - 2014 24611804
    10 - 2756 - 390 - 2014 24611804
    10 - 2620 - 347 - 2014 24611804
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic
    text
  • cCARKD remains in the cytosol, whereas mCARKD and spCARKD are targeted to the mitochondria and the endoplasmic reticulum respectively
  • basic FUNCTION
  • protein with a predicted mitochondrial propeptide (mCARKD), a signal peptide (spCARKD) or neither of them (cCARKD)
  • dehydratase, that reacts only with the S-epimer of NAD(P)HX
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS