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FLASH GENE
Symbol NANOS1 contributors: npt/ - updated : 04-02-2005
HGNC name nanos homolog 1 (Drosophila)
HGNC id 23044
Location 10q26.11      Physical location : 120.789.227 - 120.793.854
Synonym name
  • nanos homolog 1
  • EC_Rep1a
  • Synonym symbol(s) NOS1, NOS-1
    DNA
    TYPE functioning gene
    STRUCTURE 4.63 kb     1 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 4627 - 292 - Jaruzelska (2003)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    Skeletonaxial skeletonskullfacemaxilla 
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatocyte
    Reproductivespermatogonia
    Skin/Tegumentmelanocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text eye
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one nanos-type zinc finger
  • HOMOLOGY
    Homologene
    FAMILY
  • nanos family
  • CATEGORY RNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    text concentrated in the perinuclear region
    basic FUNCTION
  • may regulate translation of specific mRNAs by forming a complex with PUM2 that associates
  • with the 3' untranslated regions (UTRs) of mRNA targets
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacting with PUM2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS