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FLASH GENE
Symbol NANOGP8 contributors: npt - updated : 14-12-2015
HGNC name NANOG homeobox pseudogene 8
HGNC id 23106
Location 15q14      Physical location : -
Synonym symbol(s) NANOG, MGC119250, NANOGP1, PN8
DNA
TYPE pseudogene
SPECIAL FEATURE
text
  • could be a retrogene
  • ectopic expression of NANOGP8 generates the functional protein
  • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - - - 305 - 2012 22079639
  • structurally very similar to the NANOG gene product, and is expressed in human cells
  • major form expressed in many types of cancer, promotes stem
  • cell-like characteristics, and facilitates progression of cancer
    EXPRESSION
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • expressed pseudogene that may play important roles in tumorigenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in cancers
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS