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FLASH GENE
Symbol NANOGP1 contributors: mct - updated : 06-01-2015
HGNC name Nanog homeobox pseudogene 1
HGNC id 23099
Location 12p13.31      Physical location : -
Genatlas name Nanog homeobox 2
Synonym name homeobox protein NANOG2
Synonym symbol(s) NANOG2
DNA
TYPE functioning gene
SPECIAL FEATURE arranged in tandem
text a tandem duplication of NANOG
STRUCTURE 26.36 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text
  • transcripts containing exon 1b/1b* sequences, but exon 1a could be identified in the genomic DNA (PMID: 20427424)
  • identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing - 29 - - 2010 20427424
    exhibit the skipping of the first 48 nt of exon 6
    - splicing - 29 - - 2010 20427424
  • comprises transcripts that use either exon 1b or 1b*
  • exhibit the skipping of the first 48 nt of exon 6
  • - splicing - 27 - - 2010 20427424
  • fuses exon 1b with exon 4, resulting in an open reading frame
  • exhibit the skipping of the first 48 nt of exon 6
  • - splicing - 19 - - 2010 20427424
  • nearly identical to splice variant D2, however, exon 3 is fused to nt +39 of exon 4
  • exhibit the skipping of the first 48 nt of exon 6
  • displayed a partial loss of the Homeobox domain
  • EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemplacenta    Homo sapiens
     male systemprostate    Homo sapiens
    Respiratorylung     Homo sapiens
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte Homo sapiens
    cell lineage transcribed in CD34+
    cell lines different leukemia cells
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • Nanog homeobox family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS