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FLASH GENE
Symbol NAA11 contributors: mct - updated : 07-07-2008
HGNC name N(alpha)-acetyltransferase 11, NatA catalytic subunit
HGNC id 28125
Location 4q21.21      Physical location : 80.238.272 - 80.247.171
Synonym name
  • N-terminal acetyltransferase complex ARD1 subunit homolog B
  • human arrest defective 2
  • ARD1 homolog B (S. cerevisiae)
  • Synonym symbol(s) ARD2, MGC10646, ARD1B
    EC.number 2.3.1.88
    DNA
    TYPE functioning gene
    STRUCTURE 8.90 kb     2 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 1549 25 229 - 2006 16638120
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemplacenta  highly
    Skin/Tegumentskin   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to ARD1A (81 p100)
    Homologene
    FAMILY
  • acetyltransferase family
  • ARD1 subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • potentially complements the functions of ARD1A, adding more flexibility and complexity to protein N-alpha-acetylation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • potentially interacts with NARG1, suggesting that ARD1B-NARG1 complexes may be responsible for protein N-alpha-acetylation in human cells
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS