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FLASH GENE
Symbol MYO1D contributors: - updated : 28-03-2006
HGNC name myosin ID
HGNC id 7598
Location 19p13.3-p13.2      Physical location : 30.819.627 - 31.203.902
Synonym symbol(s) KIAA0727, myr4
DNA
TYPE functioning gene
STRUCTURE 384.00 kb     22 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 mouthtongue  highly
Hearing/Equilibriumearinnercochlea  
Nervousbrain   highly
Reproductivefemale systemovary  highly
Respiratoryrespiratory tractlarynx  highly
 respiratory tracttrachea  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal motor domain with ATP and actin-binding sites
  • a neck containing two IQ calmodulin or calmodulin-like light chain binding domains
  • a tail with two TH and one SH3 motifs
  • a myosin head-like domain
  • a C terminal globular domain
  • HOMOLOGY
    interspecies homolog to murine Myo1f
    Homologene
    FAMILY myosin family
    CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • unconventional, apparently non filamentous, actin-based motor molecules with ATPase activity
  • playing a role in intracellular movements
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling sensory transduction/hearing
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds calmodulin through its IQ motifs
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS