SUBCELLULAR LOCALIZATION
| plasma membrane
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| intracellular
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| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endosome
|
| intracellular,cytoplasm,organelle,lysosome
|
| intracellular,cytoplasm,cytoskeleton
|
text
| concentrates on endosomal and ruffling membranes |
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associates with the plasma membrane and certain subcellular organelles such as endosomes and lysosomes |
basic FUNCTION
| participating in process critical to neuronal development |
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functioning such as cell migration, neurite outgrowth and vesicular transport |
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controls the traffic of protein cargo in multivesicular endosomes most probably through its ability to modulate with actin the morphology of these sorting endosomes |
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play roles in membrane trafficking and dynamics |
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may play a role in the local midgut response pathway of the Imd innate immune response to Gram-negative bacterial infection |
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is substantially more tension-sensitive than other myosins with similar length lever arms, indicating that different myosins have different tension-sensitive transitions |
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regulates the actin-dependent post-Golgi traffic of cargo, generates force that controls the assembly of F-actin foci and, together with the actin cytoskeleton, promotes the formation of tubules at the trans-Golgi network |