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FLASH GENE
Symbol MYL7 contributors: npt/ - updated : 10-05-2004
HGNC name myosin, light chain 7, regulatory
HGNC id 21719
Location 7p13      Physical location : 44.178.464 - 44.180.916
Synonym name
  • likely ortholog of mouse myosin light chain, regulatory A
  • myosin, light polypeptide 7, regulatory
  • myosin light chain 2a
  • myosin regulatory light chain 2, atrial isoform
  • Synonym symbol(s) MYL2A, MYLC2A
    DNA
    TYPE functioning gene
    STRUCTURE 2.45 kb     7 Exon(s)    1 Copie(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    HIP-55 7p13 src homology 3 domain-containing protein HIP-55 LOC393058 7 similar to OG-2 homeodomain protein-like; similar to U65067 (PID:g1575526) PGAM2 7p13-p12 phosphoglycerate mutase 2 (muscle) POLM 7p13 polymerase (DNA directed), mu LOC393059 7 similar to peptidyl-Pro cis trans isomerase AEBP1 7p15.1 AE binding protein 1 TPK1 7q34 thiamin pyrophosphokinase 1 POLD2 7p15.1 polymerase (DNA directed), delta 2, regulatory subunit 50kDa BLVRA 7p14-cen biliverdin reductase A MYL7 7p21-p11.2 myosin, light polypeptide 7, regulatory GCK 7p14-p13 glucokinase (hexokinase 4, maturity onset diabetes of the young 2) YKT6 7p15.1 SNARE protein Ykt6 CAMK2B 7p13 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta MRPS24 7p14 mitochondrial ribosomal protein S24 URG4 7p13 up-regulated gene 4 LOC51619 7p13 ubiquitin-conjugating enzyme HBUCE1 LOC389486 7 similar to RAS p21 protein activator 4; GTPase activating protein-like; Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator WBSCR19 7q11.23 Williams Beuren syndrome chromosome region 19 KIAA1068 7p13-p12 Williams Beuren syndrome chromosome region 19 LOC392023 7 similar to RasGAP-activating-like protein 2 (Calcium-promoted Ras inactivator) HIP-55 7p13 src homology 3 domain-containing protein HIP-55 PGAM2 7p13-p12 phosphoglycerate mutase 2 (muscle) POLM 7p13 polymerase (DNA directed), mu AEBP1 7p15.1 AE binding protein 1 POLD2 7p15.1 polymerase (DNA directed), delta 2, regulatory subunit 50kDa MYL7 7p21-p11.2 myosin, light polypeptide 7, regulatory NPC1L1 7p13 NPC1 (Niemann-Pick disease, type C1, gene)-like 1 GCK 7p14-p13 glucokinase (hexokinase 4, maturity onset diabetes of the young 2) DDX56 7p13 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 YKT6 7p15.1 SNARE protein Ykt6 HNLF 7p13 putative NFkB activating protein HNLF CAMK2B 7p13 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta OGDH 7p14-p13 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) LOC393060 7 similar to Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) LOC393061 7 similar to ribosomal protein L7 DKFZp761I2123 7p13 hypothetical protein DKFZp761I2123 KIAA1068 7p13-p12 hypothetical protein DKFZp761I2123 PPIA 7p13-p11.2 peptidylprolyl isomerase A (cyclophilin A) H2AV 7p13 H2A histone family, member V NPC1L1 7p13 NPC1 (Niemann-Pick disease, type C1, gene)-like 1 PURB 7p13 purine-rich element binding protein B DDX56 7p13 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 619 19.32 175 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheartatrium  predominantly
    Digestivepancreas exocrine    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophilic
    STRUCTURE
    motifs/domains
  • two potential phosphorylation sites
  • one EF-hand calcium binding domain
  • mono polymer heteromer , hexamer
    HOMOLOGY
    interspecies homolog to murine Mylc2a
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • ATPase activity
  • micro filament motor activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
  • Ca2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS