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FLASH GENE
Symbol MYL6 contributors: npt/ - updated : 10-01-2006
HGNC name myosin, light chain 6, alkali, smooth muscle and non-muscle
HGNC id 7587
Location 12q12      Physical location : 56.552.099 - 56.555.366
Synonym name
  • myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
  • myosin light chain alkali 3
  • myosin light polypeptide 6
  • Synonym symbol(s) ESMLC, LC17A, LC17B, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM
    DNA
    TYPE functioning gene
    STRUCTURE 3.27 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    DNAJ 12q13.13 DnaJ protein MMP19 12q14 matrix metalloproteinase 19 PYM 12q13.13 PYM protein DGKA 12q13.3 diacylglycerol kinase, alpha 80kDa SILV 12q13-q14 silver homolog (mouse) CDK2 12q13.3 cyclin-dependent kinase 2 SUOX RAB5B 12q13 RAB5B, member RAS oncogene family ZNFN1A4 12q13 zinc finger protein, subfamily 1A, 4 (Eos) RPS26 12q14 ribosomal protein S26 ERBB3 12q13.3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) PA2G4 12q13 proliferation-associated 2G4, 38kDa RPL41 12q14 ribosomal protein L41 FLJ14451 12q13.13 hypothetical protein FLJ14451 MBC2 12q13.13 hypothetical protein FLJ14451 MLC1SA 12q13.13 hypothetical protein FLJ14451 MYL6 12q12 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle SMARCC2 12q13-q14 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 RNF41 12q13.13 ring finger protein 41 MGC2731 12q13.13 hypothetical protein MGC2731 SLC39A5 12q13.3 solute carrier family 39 (metal ion transporter), member 5 FLJ34236 12q13.13 hypothetical protein FLJ34236 FLJ32452 12q13.13 hypothetical protein FLJ32452 CS 12p11-qter citrate synthase TMEM4 12q15 transmembrane protein 4 USP52 12q13.2-q13.3 ubiquitin specific protease 52 APOF 12q13.13 apolipoprotein F IL23A 12q13.2-q13.3 interleukin 23, alpha subunit p19 STAT2 17q11.1-q22 signal transducer and activator of transcription 2, 113kDa LOC390331 12 similar to hypothetical protein FLJ10560 TIMELESS 12q12-q13 timeless homolog (Drosophila)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 704 16.8 151 - Lenz (1989)
    lack exon 3
    6 - 713 16.8 116 - Lenz (1989)
    lack exons 3-7
    - - 674 13 116 - Lenz (1989)
    lack exons 1-3
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Cardiovascularheart    
    Endocrinepancreas    
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    Muscularsmooth   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text pancreas
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • EF-hand, calcium binding motif
  • mono polymer hexamer
    HOMOLOGY
    interspecies homolog to murine Myln
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be modulating the interaction between myosin and actin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS