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FLASH GENE
Symbol MYH13 contributors: npt/ - updated : 02-06-2007
HGNC name myosin, heavy chain 13, skeletal muscle
HGNC id 7571
Location 17p13.1      Physical location : 10.204.182 - 10.276.322
Synonym name
  • myosin, heavy polypeptide 13, skeletal muscle
  • extraocular muscle myosin heavy chain
    • Synonym symbol(s) MyHC-eo
    DNA
    TYPE functioning gene
    STRUCTURE 72.14 kb     41 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map see MYH1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    41 - 5992 223.5 1938 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Respiratoryrespiratory tractlarynx   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatum   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • made of a globular head associating to the light chain
  • actin and ATP binding sites
  • a neck containing IQ calmodulin or calmodulin-like light chain binding domain (the converter) connected to the base of a long alpha helical tail, (the liver)
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • motor contractile protein moving towards the "plus" end of actin track
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS