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FLASH GENE
Symbol MUC7 contributors: npt/ - updated : 20-09-2006
HGNC name mucin 7, secreted
HGNC id 7518
Location 4q13.3      Physical location : 71.296.208 - 71.348.713
Synonym name mucin 7, salivary
Synonym symbol(s) MG2, FLJ27047, Apo-MG2, DKFZp686J03256, MGC34772
DNA
TYPE functioning gene
STRUCTURE 10.78 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status provisional
Physical map
LOC391668 4 similar to RSDK2559 UGT2B25P 4q13 UDP glycosyltransferase 2 family, polypeptide B25 pseudogene UGT2B24P 4q13 UDP glycosyltransferase 2 family, polypeptide B24 pseudogene LOC389209 4 LOC389209 UGT2B4 4q13 UDP glycosyltransferase 2 family, polypeptide B4 UGT2A1 4q13 UDP glycosyltransferase 2 family, polypeptide A1 SULT1B1 4q13 sulfotransferase family, cytosolic, 1B, member 1 SULT1D1P 4q13.3 sulfotransferase family, cytosolic, 1B, member 1 STE 4q13.1 sulfotransferase, estrogen-preferring CSN1S1 4q21.1 casein alpha s1 CSN2 4q13.1-q21.1 casein beta STATH 4q11-q13 statherin HTN3 4q13 histatin 3 HTN1 4q13.3 histatin 1 FLJ20513 C4orf7 4q13 chromosome 4 open reading frame 7 CSN3 4q13.1-q21.1 casein kappa NYD-SP26 4q13.3 testis development protein NYD-SP26 PROL5 4q13.2 proline rich 5 (salivary) PROL3 4q13.3 proline rich 3 PROL1 4q13.2 proline rich 1 MUC7 4q13-q21 mucin 7, salivary ENAM 4q11-q21 enamelin IGJ 4q21 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides SAS10 4q13.3 disrupter of silencing 10 RIPX 4q21.1 rap2 interacting protein x GRSF1 4q13 G-rich RNA sequence binding factor 1 MOB4A DCK 4q13.1-q21.1 deoxycytidine kinase SLC4A4 4q21 solute carrier family 4, sodium bicarbonate cotransporter, member 4
RNA
TRANSCRIPTS type messenger
text Transcript 1, 2 and 3 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2565 37 377 - Bobek (1996)
- - 2504 37 377 - Bobek (1996)
- - 2467 37 377 - Bobek (1996)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
respiratorylungbronchi   
cell lineage
cell lines
fluid/secretion saliva
at STAGE
physiological period fetal
Text tracheal,bronchi
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • unique N and C terminal regions
  • five potential sites for N glycosylation
  • a central tandem repeat domains comprising six copies (23AA) in the common allele most
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme , immunity/defense , secretory
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text facilitating the cleavance of oral bacteria
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in bladder cancer during the malignant transformation of bladder urothelium
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS