Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MTNR1A | contributors: mct - updated : 21-11-2012 |
HGNC name | melatonin receptor 1A |
HGNC id | 7463 |
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Location | 4q35.2 Physical location : 187.454.808 - 187.476.537 |
Synonym symbol(s) | MEL-1A-R, MT1 |
DNA |
TYPE | functioning gene |
STRUCTURE | 21.73 kb 2 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY | G protein coupled receptor superfamily |
CATEGORY | receptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria | |
text |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | circadian , reproduction/sex |
text | |
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PATHWAY |
metabolism |
signaling | hormonal |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
activated by | melatonin that is involved in the regulation of adrenal glucocorticoid production in diurnal primates through activation of MTNR1A membrane-bound melatonin receptors |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
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Variant & Polymorphism | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |