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FLASH GENE
Symbol MT-TP contributors: mct - updated : 18-05-2021
HGNC name mitochondrially encoded tRNA proline
HGNC id 7494
Location mt      Physical location : -
Synonym name tRNA proline
Synonym symbol(s) MTTP, TRNP
DNA
TYPE small rna
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type untranslated
EXPRESSION
Rna function
  • importance of MT-TP mutations as a cause of mitochondrial muscle disease
    • Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional germinal mutation      
    5 MT-TP mutations have been reported as a cause of mitochondrial muscle disease
    constitutional germinal mutation      
    in progressive external ophthalmoplegia due to a recurrent de novo m.15990C>T MT-TP (mt-tRNA Pro) gene variant
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS