Selected-GenAtlas references SOURCE GeneCards NCBI Gene Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol MT-TL1 contributors: mct/npt - updated : 18-05-2011
HGNC name mitochondrially encoded tRNA leucine 1 (UUA/G)
HGNC id 7490
Corresponding disease
MELAS mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome
MERRF myoclonic epilepsy associated with ragged-red fibers
MTDM mitochondrial diabetes mellitus with deafness
Location mt      Physical location : -
Synonym name tRNA leucine 1 (UUA/G)
Synonym symbol(s) MTTL1, TRNL1
DNA
TYPE functioning gene
STRUCTURE 0.75 kb     1 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s) MELAS , MERRF , MTDM
Susceptibility to maternal inherited diabetes with hearing loss
Variant & Polymorphism other mutation increasing the risk of maternal inherited diabetes with hearing loss
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS