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FLASH GENE
Symbol MS4A5 contributors: - updated : 24-02-2004
HGNC name membrane-spanning 4-domains, subfamily A, member 5
HGNC id 13374
Location 11q12      Physical location : 60.197.061 - 60.215.259
Synonym name testis expressed in transmembrane proteins/CD20 antigen-like 2
Synonym symbol(s) CD20L2,TETM4
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 18.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
LOC390195 11 similar to Olfactory receptor 5AN1 LOC390196 11 similar to seven transmembrane helix receptor LOC219981 11q12.2 similar to Olfactory receptor 5A2 LOC219982 11q12.2 similar to Olfactory receptor 5A1 (OST181) LOC219983 11q12.2 similar to Olfactory receptor 4D6 LOC390197 11 similar to seven transmembrane helix receptor LOC390198 11 similar to seven transmembrane helix receptor LOC219986 11q12.2 similar to seven transmembrane helix receptor LOC390199 11 similar to Olfactory receptor 4D9 LOC390200 11 similar to olfactory receptor MOR239-1 OSBP 11q12.2 oxysterol binding protein FLJ36874 11q12.2 hypothetical protein FLJ36874 LOC390201 11 similar to seven transmembrane helix receptor LOC390202 11 similar to olfactory receptor GA_x6K02T2RE5P-2207258-2206302 STX3A 11q12.1 syntaxin 3A MRPL16 11q12-q13.1 mitochondrial ribosomal protein L16 GIF 11q12.2 gastric intrinsic factor (vitamin B synthesis) TCN1 11q11-q12 transcobalamin I (vitamin B12 binding protein, R binder family) LOC390203 11 similar to hypothetical protein FLJ13352 LOC255649 11q12.2 hypothetical LOC255649 FLJ36198 11q12.2 hypothetical protein FLJ36198 MS4A3 11q12 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) MS4A2 11q12.2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) MS4A6A 11q12.1 membrane-spanning 4-domains, subfamily A, member 6A LOC390204 11 similar to membrane-spanning 4-domains, subfamily A, member 4 isoform b; membrane-spanning 4-domains, subfamily A, member 4A; four-span transmembrane protein; Fc epsilon receptor beta subunit homolog MS4A4A 11q12 membrane-spanning 4-domains, subfamily A, member 4 MS4A6E 11q12.1 membrane-spanning 4-domains, subfamily A, member 6E MS4A7 11q12.1 membrane-spanning 4-domains, subfamily A, member 7 NYD-SP21 11q12.2 testes development-related NYD-SP21 MS4A5 11q12 membrane-spanning 4-domains, subfamily A, member 5 MS4A1 11q12.2-q13.1 membrane-spanning 4-domains, subfamily A, member 1 MS4A12 11q12.1 membrane-spanning 4-domains, subfamily A, member 12 MGC39681 11q12.2 hypothetical protein MGC39681 MS4A8B 11q12.1 membrane-spanning 4-domains, subfamily A, member 8B MGC35295 11q12.2 hypothetical protein MGC35295 LOC341116 11q12.2 similar to Membrane-spanning 4-domains subfamily A member 10 MGC2574 11q12.2 hypothetical protein MGC2574 GPR44 11q12-q13.3 G protein-coupled receptor 44 LOC255714 11q12.2 similar to ZP1 precursor NMP200 11q12.2 nuclear matrix protein NMP200 related to splicing factor PRP19 MGC5508 11q12.2 hypothetical protein MGC5508 GBP 11q12.2 likely ortholog of rat GRP78-binding protein SLC15A3 11q13.1 solute carrier family 15, member 3 CD6 11q13 CD6 antigen CD5 11q12.2 CD5 antigen (p56-62) FLJ20847 11q12.3 hypothetical protein FLJ20847 PGA5 11q13 pepsinogen 5, group I (pepsinogen A) FLJ32009 11q12.3 hypothetical protein FLJ32009 DDB1 11q12-q13.1 damage-specific DNA binding protein 1, 127kDa DKFZP586B1621 11q12.3 DKFZP586B1621 protein MGC20446 11q12.3 hypothetical protein MGC20446
RNA
TRANSCRIPTS type messenger
text splice variants
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
transmembrane (TM) protein comprising a short intracellular domain,four transmembrane segments (4TM) and a long cytoplasmic tail,involved in intracellular signaling
HOMOLOGY
interspecies homolog to murine Ms4a2
Homologene
FAMILY membrane-spanning 4-domains,subfamily A
CATEGORY signaling , receptor membrane
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION involved in the regulation of B cell activation and proliferation
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS immunity/defense
PATHWAY
metabolism
signaling signal transduction
a component component of oligomeric cell surface complex involved in signal transduction
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS