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FLASH GENE
Symbol MRPS11 contributors: - updated : 30-05-2006
HGNC name mitochondrial ribosomal protein S11
HGNC id 14050
Location 15q25      Physical location : 89.010.683 - 89.021.494
Synonym name
  • cervical cancer proto-oncogene 2
  • 28S ribosomal protein S11, mitochondrial precursor
  • Synonym symbol(s) FLJ22512, FLJ23406, HCC-2, S11mt
    DNA
    TYPE functioning gene
    STRUCTURE 10.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1136 20 194 - -
  • isoform a
  • - - 1053 16 161 - -
  • lacking an internal in-frame segment
  • isoform b
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated RiboP
    HOMOLOGY
    interspecies homolog to E.Coli 30S subunit proteins
    Homologene
    FAMILY ribosomal protein S11 family
    CATEGORY structural protein , RNA associated , protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the small subunit (28S) of the mitochondrial ribosome, including two RNA molecules and 78 MRPs among which 31proteins for the small subunit
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral        
    cervical carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS