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FLASH GENE
Symbol MRPL49 contributors: - updated : 05-04-2006
HGNC name mitochondrial ribosomal protein L49
HGNC id 1176
Location 11q13      Physical location : 64.889.727 - 64.894.841
Synonym name
  • neighbor of FAU
  • next to FAU
    • Synonym symbol(s) NOF, NOF1, L49mt, MGC10656, C11orf4
    DNA
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
    STRUCTURE 5.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map see FAU
    regionally located neighbour of FAU, in opposite orientation
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
    Endocrineadrenal gland   highly
     pancreas   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    		open reading frame of 166 AA,proline rich without homology with any known gene,four putative transmembrane domain (4TM) signal peptides at the N and C termini
    HOMOLOGY
    interspecies ortholog to mouse NOF, Drosophila, C Elegans, S cerevisiae mitochondrial ribosomal protein
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosoma
    basic FUNCTION regulator of C3 convertase of classical pathway
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS