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FLASH GENE
Symbol MRPL4 contributors: - updated : 16-12-2005
HGNC name mitochondrial ribosomal protein L4
HGNC id 14276
Location 19p13.2      Physical location : 10.362.639 - 10.370.734
Synonym symbol(s) CGI-28, L4mt, MGC2681, MGC16367
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1511 - 311 - Suzuki
- splicing 1375 - 311 - Suzuki
- - 2404 - 263 - Suzuki
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to chimpanzee LOC455697
ortholog to murine Mrpl4
ortholog to rattus mrpl4
Homologene
FAMILY
CATEGORY structural protein , RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
text mitochondrial ribosome
basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the large subunit (39S) of the mitochondrial ribosome, including two RNA molecules and, at least,70 MRPs among which 47 proteins for the large subunit
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS