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FLASH GENE
Symbol MRPL20 contributors: mct - updated : 13-07-2021
HGNC name mitochondrial ribosomal protein L20
HGNC id 14478
Location 1p36.33      Physical location : 1.337.276 - 1.342.693
Synonym name 39S ribosomal protein L20, mitochondrial
Synonym symbol(s) FLJ10024, L20-mt, MGC4779, MGC74465, MRP-L20
DNA
TYPE functioning gene
STRUCTURE 5.41 kb     4 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 700 17.31 149 - 2001 11551941
4 - 1045 - 102 - 2001 11551941
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to E Coli (50S), Drosophila, C Elegans, S Cerevisiae mitochondrial protein
Homologene
FAMILY
CATEGORY structural protein , RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
intracellular,cytoplasm,organelle,mitochondria,matrix
intracellular,cytoplasm,organelle,membrane
text mitochondrial ribosome
basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • MRPL20, which cross-links to human OXA1L-CTT, is missing in yeast mitochondrial ribosomes
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the large subunit (39S) of the mitochondrial ribosome, including two RNA molecules and, at least, 70 MRPs among which 47 proteins for the large subunit
  • INTERACTION
    DNA
    RNA mRNAs
    small molecule
    protein
  • OXA1L-C-terminal approximately 100-amino acid tail of OXA1L (Oxa1L-CTT) cross-links to mammalian mitochondrial homologs of the bacterial ribosomal proteins RPL13, RPL20, and RPL28
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS