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FLASH GENE
Symbol MRPL13 contributors: mct - updated : 27-05-2013
HGNC name mitochondrial ribosomal protein L13
HGNC id 14278
Location 8q22.1-q22.3      Physical location : 121.408.083 - 121.457.647
Synonym symbol(s) L13, RPL13
DNA
TYPE functioning gene
STRUCTURE 49.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
EXT1 8q24.11 exostoses (multiple) 1 LOC392263 8 similar to RIKEN cDNA A830094I09 gene LOC286091 8q24.12 similar to 40S ribosomal protein S26 TNFRSF11B 8q24.13 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) COLEC10 8q24.13 collectin sub-family member 10 (C-type lectin) MAL2 8q23 mal, T-cell differentiation protein 2 NOV 8q24.1 nephroblastoma overexpressed gene LOC392264 8 hypothetical gene supported by AK122835 ENPP2 8q24.13 ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) HCP23 8q24.12 cytochrome c, somatic pseudogene TAF2 8q24.12 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa MGC5528 8q24.12 defective in sister chromatid cohesion homolog 1 (S. cerevisiae) MGC14407 8q24.12 hypothetical protein MGC14407 FLJ12428 8q24.12 hypothetical protein FLJ12428 LOC389682 8 similar to collagen type XIV COL14A1 8q24.13 collagen, type XIV, alpha 1 (undulin) MRPL13 8q22.1-q22.3 mitochondrial ribosomal protein L13 MTBP 8q24.1-q24.2 Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa SNTB1 8q24.13 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) HAS2 8q24.13 hyaluronan synthase 2 MRPS36P3 8q24.13 mitochondrial ribosomal protein S36 pseudogene LOC389683 8 LOC389683 LOC392265 8 similar to Cell division protein kinase 5 (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine protein kinase PSSALRE) LOC389684 8 LOC389684 ZHX2 8q24.13 zinc fingers and homeoboxes 2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Mrpl13
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
text mitochondrial ribosome
basic FUNCTION
  • involved in mitochondrial proteins biosynthesis, ribosomal structure and biogenesis
  • ribosomal protein exclusively found in mitochondria (
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the large subunit (39S) of the mitochondrial ribosome, including two RNA molecules and, at least 70 proteins among which 47 proteins fir the large subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS