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FLASH GENE

Symbol

MRGPRX1

contributors: mct - updated : 07-12-2011

HGNC name	MAS-related GPR, member X1
HGNC id	17962

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	11p15.1      Physical location : 18.955.360 - 18.956.549
Synonym name	MAS-related gene
	sensory neuron-specific G protein--coupled receptors 4
	G protein-coupled receptor MRGX1
Synonym symbol(s)	GPCR, SNSR4, MRGX1, MrgprC11

DNA

TYPE	functioning gene
STRUCTURE	1.19 kb     1 Exon(s)

regulatory sequence

Promoter

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_147199 1 - 1190 - 322 - 2002 11850634

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

embryo

Text

liver

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

transmembrane, extracellular, and cytoplasmic domains

HOMOLOGY

Homologene

FAMILY	G-protein coupled receptor 1 family
	Mas subfamily

CATEGORY

receptor membrane G

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm

basic FUNCTION	may regulate nociceptor function and/or development, including the sensation or modulation of pain
	may be playing a role in sensory neuron regulation and in the modulation of nociception
	c

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS