basic FUNCTION
| potentially involved as homotypic adhesion molecule in thymus histogenesis |
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CD3-binding immunoglobulin-like protein, regulates embryonic thymic development |
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modulation of MPZL2 expression in thymocytes is crucial for lymphocyte physiological developmental progression and stromal differentiation |
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immunoglobulin-like adhesion molecule, playing a role in structural organisation of the thymus and early lymphocyte development |
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lysosome and endoplasmic reticulum-associated protein involved in autophagy and apoptosis |
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MPZL2- induced autophagy and apoptosis play a role in suppressing the development of glioblastoma (GBM) |
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adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues |
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has likely a unique function in the inner ear |
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MPZL2 function is essential only in the inner ear and functional redundancy might well prohibit phenotypic effects in other tissues |