protein
| targets myosin phosphatase to the contractile apparatus to dephosphorylate myosin light chains |
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interferes with RHOA-mediated transcription through its ability to disassemble the actomyosin cytoskeleton downstream of RHOA |
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MAPK8 target gene, is myosin phosphatase-Rho interacting protein (MPRIP) |
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NUAK2 is a second protein targeted by MPRIP to actin fibers (NUAK2-MPRIP association inhibits fiber disassembly and MYPT1-mediated MLC dephosphorylation) |
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SDCBP controls RAC1 through a specific association with the myosin phosphatase Rho interacting protein (MPRIP), which occurs in response to phosphorylation of SDCBP by SRC at Tyr4 |
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interaction of PPP1R12A and myosin phosphatase-RHOA interacting protein (MRIP), causes co-localization of myosin phosphatase and RHOA to actomyosin |
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