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FLASH GENE
Symbol MPHOSPH10 contributors: npt/ - updated : 23-09-2004
HGNC name M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
HGNC id 7213
Location 2p13.3      Physical location : 71.357.443 - 71.377.230
Synonym name M phase phosphoprotein 10
Synonym symbol(s) MPP10, MPP-10, MPP10P
DNA
TYPE functioning gene
STRUCTURE 19.79 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 2503 78.7 681 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrinepancreas   highly
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
cell cycle     cell cycle, M
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated RiboP , PhosphoP
HOMOLOGY
Homologene
FAMILY
  • MPP10 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    text fibrillar region of nucleole
    basic FUNCTION
  • acting as a component of U3 small nucleolar ribonucleoprotein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of a heterotrimeric complex containing IMP3, IMP4 and KIF20B (Granneman 2003)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • IMP3
  • IMP4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS