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FLASH GENE
Symbol MPG contributors: - updated : 20-05-2005
HGNC name N-methylpurine-DNA glycosylase
HGNC id 7211
Location 16p13.3      Physical location : 127.017 - 135.841
Synonym name
  • 3-alkyladenine DNA glycosylase
  • methyl adenine DNA glycosylase
    • Synonym symbol(s) DGMA, MDG
    EC.number 3.2.2.21
    DNA
    TYPE functioning gene
    STRUCTURE 6.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map pter - IL9RP3 - MPG - LCR-HBA@ - HB-A@ - D16S60 - D16S215 - D16S213 - D16S53 - cen
    Authors Deng (92), Flint (97)
    regionally located 75kb upstream HBZ
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines highly in adenocarcinoma cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • DNA glycosylase, 3-methyl-adenine,base excision repair
  • functioning as a trranscriptional repressor
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding damage DNA
    RNA
    small molecule
    protein
  • RAD23 (damage recognition proteins in excision repair pathways)
  • MBD1
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS