Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol MGAM contributors: mlc - updated : 14-12-2007
HGNC name maltase-glucoamylase (alpha-glucosidase)
HGNC id 7043
Corresponding disease
MGAM diarrhea in children
Location 7q34      Physical location : 141.695.678 - 141.806.546
Synonym name
  • alpha-glucosidase
  • brush border hydrolase
  • Synonym symbol(s) MG, MGA
    EC.number 3.2.1.3 ; 3.2.1.20
    DNA
    TYPE functioning gene
    SPECIAL FEATURE head to head
    STRUCTURE 110.00 kb     48 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Map cen - D7S655 - D7S650 - MGAM MGAM - D7S2434 - D7S490 - D7S686 - D7S2473 - qter
    Authors GeneMap (98),LDB (99)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    48 - 6513 - 1857 - Ao(2007)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine   
    Lymphoid/Immunespleen    
    Reproductivemale systemtestis   
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N terminal and the C terminal catalytic sites, two catalytic sites identical to those of sucrase-isomaltase
  • 2 P-type (trefoil) domains
  • HOMOLOGY
    Homologene
    FAMILY member of the glucosyl hydrolase family 31
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • playing a unique role in the digestion of malted dietary oligosaccharides
  • brush border membrane enzyme that plays a role in the final steps of digestion of starch
  • may play a unique role in the digestion
  • of malted dietary oligosaccharides used in food manufacturing
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MGAM
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS