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FLASH GENE
Symbol MESDC1 contributors: mct - updated : 15-02-2011
HGNC name mesoderm development candidate 1
HGNC id 13519
Location 15q25.1      Physical location : 81.293.294 - 81.296.344
Synonym symbol(s) MGC99595
DNA
TYPE functioning gene
STRUCTURE 2.37 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 3068 37.6 362 - 2010 20610383
EXPRESSION
Rna function mRNA is widely expressed
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Digestiveliver    
Nervousbrain    
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal region (residues 143) has no homologues
  • homology with TLN1 is restricted to 301 AAs at the C terminus
  • secondary structure
  • secondary structure predictions suggest that the N-ter region forms a 24-AAs-long helix
  • secondary structure prediction clearly indicates that AAs 44352 have a similar secondary structure to TLN1 AAs 13591659
  • HOMOLOGY
    interspecies homolog to murine Mesdc1
    intraspecies homolog to talin AAs 13591659 in the central rod
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • actin-binding protein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS