basic FUNCTION
| may be having a role in tumor angiogenesis |
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involved in transcription regulation, DNA-dependent |
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functioning as a negative regulator of smooth muscle cell differentiation in concert with other Mediator subunits including MED6, MED8, and MED18 within the Mediator head module |
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function as a scaffolding protein by maintaining the stability of a submodule within the head module and the components of this submodule act together in a gene regulatory program to suppress smooth muscle cell differentiation |
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actin cytoskeleton-associated protein, involved in transcriptional regulation, therefore and may serve as a multi-faceted adaptor/scaffold to relay cellular signaling to the cytoskeleton and from the cytoskeleton to the nucleus |
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implicated in transcriptional control, signal regulation, and cell proliferation and has also been associated with tumor progression |
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regulates cellular migration in a MAP2K1-dependent manner in breast cancer cells, reinforcing the important cellular roles of MED28 |