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FLASH GENE
Symbol MAST1 contributors: npt/mct - updated : 05-11-2008
HGNC name microtubule associated serine/threonine kinase 1
HGNC id 19034
Location 19p13.13      Physical location : 12.949.258 - 12.985.765
Synonym name
  • related to mus microtubule-associated S/T-protein kinase MAST205
  • syntrophin associated serine/threonine kinase
  • Synonym symbol(s) KIAA0973, SAST, SAST170
    EC.number 2.7.11.1
    DNA
    TYPE functioning gene
    STRUCTURE 36.42 kb     26 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    26 - 4833 170 1570 - Olsen (2006)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineneuroendocrinepituitary  highly
    Nervousnerve   highly
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a serine/threonine kinase domain
  • a postsynaptic density protein-95/discs large/zona occludens-1 domain (PDZ)
  • HOMOLOGY
    interspecies homolog to mus microtubule-associated S/T-protein kinase MAST205
    Homologene
    FAMILY
  • Microtubule-Associated Serine/Threonine Kinase family
  • Ser/Thr protein kinase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION playing a role in a broad range of neural functions
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS