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FLASH GENE
Symbol MAP7D3 contributors: mct - updated : 05-03-2013
HGNC name MAP7 domain containing 3
HGNC id 25742
Location Xq26.3      Physical location : 135.295.379 - 135.338.641
Synonym symbol(s) RP11-535K18.3, MDP3
DNA
TYPE functioning gene
STRUCTURE 43.26 kb     19 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
18 - 4589 - 841 - 2011 22142902
19 - 4463 - 858 - 2011 22142902
19 - 4575 - 876 - 2011 22142902
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two coiled coil motifs critical for its interaction with tubulin and microtubules
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
    intracellular,nucleus
    basic FUNCTION
  • potential microtubule-binding protein
  • important role in regulating cellular microtubule assembly
  • novel microtubule-binding protein that regulates microtubule assembly and stability
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacted with tubulin in cells, and also associated with microtubules
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS