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FLASH GENE
Symbol MALSU1 contributors: mct - updated : 15-06-2015
HGNC name mitochondrial assembly of ribosomal large subunit 1
HGNC id 21721
Location 7p15.3      Physical location : -
Synonym name
  • hypothetical protein LOC115416
  • chromosome 7 open reading frame 30
  • Synonym symbol(s) C7orf30, mtRsfA
    DNA
    TYPE functioning gene
    STRUCTURE 10.24 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 774 - 234 - 2012 22238376
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY family of DUF143 proteins
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • is potentially a human assembly and/or stability factor involved in the biogenesis of the large subunit of the mitochondrial ribosome
  • is involved in ribosomal large subunit function
  • contributes critically to mitochondrial translation and specifically associates with the large subunit of the mitochondrial ribosome (mt-LSU)
  • contributes critically to mitochondrial translation and specifically associates with the large subunit of the mitochondrial ribosome (mt-LSU), essential for mitochondrial ribosome biogenesis and mitochondrial translation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associates with the mitochondrial large ribosomal subunit (mt-LSU)
  • mitochondrial ribosomal protein MRPL14 is the specific interacting protein partner of MALSU1 in the mt-LSU
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS