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FLASH GENE
Symbol LYPD3 contributors: - updated : 22-02-2006
HGNC name LY6/PLAUR domain containing 3
HGNC id 24880
Location 19q13.32      Physical location : 43.964.945 - 43.969.831
Genatlas name GPI-anchored metastasis-associated protein homolog
Synonym symbol(s) C4.4A, B3F6, GAMAP
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
digestiveesophagus    
Digestivemouthtongue  highly
Lymphoid/Immunethymus   highly
Reproductivefemale systemplacenta  highly
 male systemprostate   
Visualeyeanterior segmentcornea  
 eyelens   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Epithelialbarrier/lininguroepithelium  
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Skin/Tegumentmelanocyte
cell lineage metastatic urothelial cancer cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ly6 antigen/UPA receptor-like domains
  • three extracellular domains
  • HOMOLOGY
    interspecies homolog to rattus metastasis-associated C4-4a
    intraspecies homolog to urokinase-type plasminogen activator receptor
    Homologene
    FAMILY LY-6 family of GPI anchored glycoprotein
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    basic FUNCTION metastasis-associated membrane protein
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS