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FLASH GENE
Symbol LY6H contributors: npt/ - updated : 26-09-2006
HGNC name lymphocyte antigen 6 complex, locus H
HGNC id 6728
Location 8q24.3      Physical location : 144.239.331 - 144.242.053
Synonym name lymphocyte antigen 6H
Synonym symbol(s) NMLY6, Ly-6H
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 2.41 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
JRK 8q24.3 jerky homolog (mouse) PSCA 8q24.2 prostate stem cell antigen HSJ001348 8q24.3 cDNA for differentially expressed CO16 gene LOC51337 8q24.3 mesenchymal stem cell protein DSCD75 ARS LOC137797 8q24.3 similar to RGTR430 LYNX1 8q24.3 similar to RGTR430 E48 GML 8q24.3 GPI anchored molecule like protein CYP11B1 8q21 cytochrome P450, family 11, subfamily B, polypeptide 1 CYP11B2 8q24.3 cytochrome P450, family 11, subfamily B, polypeptide 2 LY6E 8q24.3 lymphocyte antigen 6 complex, locus E FLJ37131 8q24.3 hypothetical protein FLJ37131 HHCM 8q24.3 Mahlavu hepatocellular carcinoma LY6H 8q24.3 lymphocyte antigen 6 complex, locus H LOC338328 8q24.3 high density lipoprotein-binding protein FLJ38705 8q24.3 hypothetical protein FLJ38705 GLI4 8q24.3 GLI-Kruppel family member GLI4 FLJ14129 8q24.3 hypothetical protein FLJ14129 LOC389691 8 LOC389691 TOP1MT 8q24.3 LOC389691 MGC3113 8q24 hypothetical protein MGC3113 RHPN1 8q24.3 rhophilin, Rho GTPase binding protein 1 LOC389692 KIAA0150 8q24.3 rhophilin, Rho GTPase binding protein 1 LOC389693 8 LOC389693 FLJ12150 8q24.3 hypothetical protein FLJ12150 LOC389694 8 similar to FLJ46354 protein PP3856 8q24.3 similar to CG3714 gene product EEF1D 13q12 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) TIGD5 8q24.3 tigger transposable element derived 5 FLJ13852 8q24.3 hypothetical protein FLJ13852 TSTA3 8q24.3 tissue specific transplantation antigen P35B KIAA0628 8q24.3 tissue specific transplantation antigen P35B
RNA
TRANSCRIPTS type messenger
text variants 2 and 3 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 950 14.54 140 - Horie (1998)
- - 1006 16.84 161 - Horie (1998)
- - 986 16.84 161 - Horie (1998)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   lowly
Nervousbrainforebraincerebral cortex highly
 braindiencephalonamygdala highly
 braindiencephalonhypothalamus highly
 brainbasal nuclei  highly
Reproductivemale systemtestis  lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Nervouscentral   
cell lineage
cell lines acute lymphoblastic leukemia cells and acute human leukemic cell line MOLT-3
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY
  • LY-6 family members of small cysteine-rich proteins
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    text attached to the membrane by a GPI-anchor
    basic FUNCTION
  • playing roles in both the central nervous and the immune system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development , immunity/defense , nervous system
    text
  • histogenesis and organogenesis
  • neurogenesis
  • cellular defense response
  • PATHWAY
    metabolism
    signaling
    a component
  • constituent of lymphocyte antigen complex
  • glycosylphosphatidylinositol (GPI)-anchored constituent of cell surface membrane
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS