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FLASH GENE
Symbol LY6H contributors: npt/ - updated : 26-09-2006
HGNC name lymphocyte antigen 6 complex, locus H
HGNC id 6728
Location 8q24.3      Physical location : 144.239.331 - 144.242.053
Synonym name lymphocyte antigen 6H
Synonym symbol(s) NMLY6, Ly-6H
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 2.41 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
text variants 2 and 3 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 950 14.54 140 - Horie (1998)
- - 1006 16.84 161 - Horie (1998)
- - 986 16.84 161 - Horie (1998)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   lowly
Nervousbrainforebraincerebral cortex highly
 braindiencephalonamygdala highly
 braindiencephalonhypothalamus highly
 brainbasal nuclei  highly
Reproductivemale systemtestis  lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Nervouscentral   
cell lineage
cell lines acute lymphoblastic leukemia cells and acute human leukemic cell line MOLT-3
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY
  • LY-6 family members of small cysteine-rich proteins
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    text attached to the membrane by a GPI-anchor
    basic FUNCTION
  • playing roles in both the central nervous and the immune system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development , immunity/defense , nervous system
    text
  • histogenesis and organogenesis
  • neurogenesis
  • cellular defense response
  • PATHWAY
    metabolism
    signaling
    a component
  • constituent of lymphocyte antigen complex
  • glycosylphosphatidylinositol (GPI)-anchored constituent of cell surface membrane
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS