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FLASH GENE

Symbol

LUC7L2

contributors: mlc - updated : 23-04-2004

HGNC name	LUC7-like 2 (S. cerevisiae)
HGNC id	21608

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	7q34      Physical location : 139.044.633 - 139.108.198
Synonym symbol(s)	CGI-74, CGI-59, FLJ10657, LUC7B2

DNA

TYPE	functioning gene
STRUCTURE	63.00 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

regulatory sequence

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 10 - 2725 - 392 - Ewing (2007)

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid       highly Nervous nerve       highly Urinary bladder       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a C2H2-type zinc finger

HOMOLOGY

interspecies

homolog to murine Luc7l2

Homologene

FAMILY

Luc7 family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles

basic FUNCTION	may bind to RNA via its Arg/Ser-rich domain
	involved in recognition of non-consensus splice donor sites

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

interacting with SCNM1

cell & other

REGULATION

Other

phosphorylated upon DNA damage, probably by ATM or ATR

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS