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Symbol LSM8 contributors: mct - updated : 07-03-2019
HGNC name LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
HGNC id 20471
Location 7q31.31      Physical location : -
Synonym name
  • MAK31-like protein
  • N-alpha-acetyltransferase 38, NatC auxiliary subunit
  • Synonym symbol(s) YJR022W, NAA38, FLJ33242
    DNA
    TYPE functioning gene
    STRUCTURE 20.01 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 12520 - 96 - 2012 22875987
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivefemale systemuterus   
     male systemprostate   
    Respiratorylung    
    Visualeyeanterior segment   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY SNRNP SM proteins family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • involved in nuclear mRNA splicing, via spliceosome
  • LSM8 controls likely nuclear accumulation of all LSM2-7 proteins
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS