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FLASH GENE
Symbol LSM6 contributors: - updated : 30-05-2005
HGNC name LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
HGNC id 17017
Location 4q31.21      Physical location : 147.096.834 - 147.111.212
Synonym name Sm protein F
Synonym symbol(s) YDR378C
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Lymphoid/Immunelymph node    
Nervous     
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • SM sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop
  • HOMOLOGY
    interspecies ortholog to rattus LOC498934
    Homologene
    FAMILY snRNP SM proteins family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play a role in U4/U6 snRNP formation
  • may form a stable heteromer present in tri-snRNP particles which are important for pre-mRNA binding
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding to the U6 snRNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS