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FLASH GENE
Symbol LRTM1 contributors: mct - updated : 06-02-2013
HGNC name leucine-rich repeats and transmembrane domains 1
HGNC id 25023
Location 3p14.3      Physical location : 54.952.384 - 54.962.072
Synonym name HT017 protein
Synonym symbol(s) HT017
DNA
TYPE functioning gene
STRUCTURE 9.71 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1309 - 345 - 2002 11756676
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonepithalamuspineal gland 
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal signal peptide resulting in extracellular localization of the LRR domain
  • a short cytoplasmic C-terminal tail containing a short stretch of acidic residues
  • HOMOLOGY
    interspecies homolog to murine Lrtm1
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • belongs to an extracellular leucine-rich-repeat–only (Elron) cluster, which includes five other LRRC proteins: LRRC38, LRRC52, LRRC55, LRTM1 and LRTM2
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS