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FLASH GENE
Symbol LRRC8D contributors: - updated : 12-05-2006
HGNC name leucine rich repeat containing 8 family, member D
HGNC id 16992
Location 1p22.2      Physical location : 90.286.572 - 90.401.987
Synonym name leucine rich repeat containing 5
Synonym symbol(s) LRRC5, FLJ10470, FLJ20403
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 114.00 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunethymus    
Nervousbrain    
Reproductivefemale systemuterus   
Respiratorylung    
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 16 extracellular leucine-rich repeats
  • four transmembrane regions
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY immunity/defense , regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be implicated in proliferation and activation of lymphocytes and monocytes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS