Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol LRRC55 contributors: mct - updated : 06-02-2013
HGNC name leucine rich repeat containing 55
HGNC id 32324
Location 11q12.1      Physical location : 56.949.220 - 56.959.188
Synonym name BK channel auxilliary gamma snit LRRC55
DNA
TYPE functioning gene
STRUCTURE 9.97 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 5407 - 341 - 2012 22547800
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain     Homo sapiensAdult
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal signal peptide resulting in extracellular localization of the LRR domain
  • a short cytoplasmic C-terminal tail containing a short stretch of acidic residues
  • HOMOLOGY
    intraspecies paralog to LRRC52, LRRC26, LRRC38
    Homologene
    FAMILY
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • LRRC52, LRRC55, and LRRC38 potentially function as LRRC26-type auxiliary subunits of BK channels
  • LRRC26 and its paralogs are structurally and functionally distinct from the beta-subunits and are a gamma family of the BK channel auxiliary proteins, which potentially regulate the channel gating properties over a spectrum of different tissues or cell types
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • belongs to an extracellular leucine-rich-repeat–only (Elron) cluster, which includes five other LRRC proteins: LRRC38, LRRC52, LRRC55, LRTM1 and LRTM2
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS