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FLASH GENE
Symbol LRRC41 contributors: npt - updated : 29-04-2003
HGNC name leucine rich repeat containing 41
HGNC id 16917
Location 1p34.1      Physical location : 46.744.072 - 46.769.038
Synonym name
  • elongin BC-interacting leucine-rich repeat protein
  • MUF1 protein
  • elongin BC-interacting leucine-rich repeat protein
  • Synonym symbol(s) MUF1, MGC126571, MGC126573, PP7759, RP4-636H5.2
    DNA
    TYPE functioning gene
    STRUCTURE 25.00 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 2960 88 812 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • leucine rich repeats (LRR)
  • BC-box motif (N terminal conserved region of SOCS box)
  • HOMOLOGY
    interspecies ortholog to murine Muf1
    Homologene
    FAMILY
  • BC-box family of proteins
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • compound of an E3 ubiquitin ligase complex
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • assembly with cullin (CUL5)/RBX1 module to reconstitute an E3 ubiquitin ligase with the VHL-elongin BC complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with elongin
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS