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FLASH GENE

Symbol

LRRC2

contributors: npt - updated : 21-07-2008

HGNC name	leucine-rich repeat-containing 2
HGNC id	14676

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	3p21.3      Physical location : 46.556.879 - 46.608.011
Synonym symbol(s)	FLJ11857

DNA

TYPE	functioning gene
SPECIAL FEATURE	gene in gene, antisens
text	LUZP3 was localized within the first intron of LRRC2 with an antiparallel transcription orientation
STRUCTURE	64.66 kb     9 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

regionally located

located in C3CER1

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 5108 43 371 - Kiss variant 2 - - 4909 - 371 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic spleen       highly Cardiovascular heart       highly Digestive liver         Endocrine pancreas         Nervous brain         Reproductive male system prostate       Respiratory lung         Urinary kidney       lowly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine   Lymphoid         Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	seven leucine-rich repeats
	two putative nuclear localization signals (NLS)

HOMOLOGY

interspecies	homolog to murine Lrrc2
	homolog to Drosophila CG13344

intraspecies

homolog to RSU1

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

basic FUNCTION

may playing a role in protein-protein interaction

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS