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FLASH GENE
Symbol LRRC2 contributors: npt - updated : 21-07-2008
HGNC name leucine-rich repeat-containing 2
HGNC id 14676
Location 3p21.3      Physical location : 46.556.879 - 46.608.011
Synonym symbol(s) FLJ11857
DNA
TYPE functioning gene
SPECIAL FEATURE gene in gene, antisens
text LUZP3 was localized within the first intron of LRRC2 with an antiparallel transcription orientation
STRUCTURE 64.66 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
TNA 3p21.3 tetranectin (plasminogen binding protein) CDCP1 3p24.3-p22.1 tetranectin (plasminogen binding protein) RIS1 3p21.3 tetranectin (plasminogen binding protein) LARS2 3p21.3 leucyl-tRNA synthetase 2, mitochondrial LIMD1 3p21.3 LIM domains containing 1 SACM1L 3p21.3 SAC1 suppressor of actin mutations 1-like (yeast) XT3 3p21.3 SAC1 suppressor of actin mutations 1-like (yeast) LZTFL1 3p21.3 leucine zipper transcription factor-like 1 CCR9 3p21.3 chemokine (C-C motif) receptor 9 FYCO1 3p21.3 FYVE and coiled-coil domain containing 1 CXCR6 3p21.3 chemokine (C-X-C motif) receptor 6 XCR1 3p21.3-p21.1 chemokine (C motif) receptor 1 LOC391533 3 similar to Vascular endothelial growth factor receptor 1 precursor (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) CCR1 3p21.31 chemokine (C-C motif) receptor 1 CCR3 3p21.31 chemokine (C-C motif) receptor 3 LTF 3p21.31 lactotransferrin TMEM7 3p21.3 transmembrane protein 7 LRRC2 3p21.3 leucine-rich repeat-containing 2 TDGF1 3p21.31 teratocarcinoma-derived growth factor 1 FLJ36525 3p21.31 hypothetical protein LOC259173 TMIE 3p21 hypothetical protein LOC259173 TSP50 3p14-p12 testes-specific protease 50 TESSP5 3p21.31 testis serine protease 5 LOC391534 3 hypothetical gene supported by AK128390 TESSP2 3p21.31 testis serine protease 2 MYL3 3p21.3 myosin, light polypeptide 3, alkali; ventricular, skeletal, slow PTHR1 3p21.3 parathyroid hormone receptor 1 MGC23918 3p21.31 hypothetical protein MGC23918 KIAA0540 3p21.31 KIAA0540 protein LOC391535 3 similar to p75-like apoptosis-inducing death domain protein PLAIDD HYPB 3p21.2-q22.2 similar to p75-like apoptosis-inducing death domain protein PLAIDD MRP63P3 3p21.31 mitochondrial ribosomal protein 63 pseudogene 3 KIF9 3p21.31 kinesin family member 9 KIAA0795 3p21.31 kinesin family member 9 PTPN23 3p21.3 protein tyrosine phosphatase, non-receptor type 23 SCAP 3p24.3-p22.1 protein tyrosine phosphatase, non-receptor type 23 FLJ20211 3p21.31 hypothetical protein FLJ20211 CSPG5 3p21.3 chondroitin sulfate proteoglycan 5 (neuroglycan C) SMARCC1 3p23-p21 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 DHX30 3p31.31 DEAH (Asp-Glu-Ala-His) box polypeptide 30 MAP4 3p21.3 microtubule-associated protein 4
regionally located located in C3CER1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 5108 43 371 - Kiss
- - 4909 - 371 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   highly
Cardiovascularheart   highly
Digestiveliver    
Endocrinepancreas    
Nervousbrain    
Reproductivemale systemprostate   
Respiratorylung    
Urinarykidney   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven leucine-rich repeats
  • two putative nuclear localization signals (NLS)
  • HOMOLOGY
    interspecies homolog to murine Lrrc2
    homolog to Drosophila CG13344
    intraspecies homolog to RSU1
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may playing a role in protein-protein interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS