Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol LONRF2 contributors: - updated : 28-11-2005
HGNC name LON peptidase N-terminal domain and ring finger 2
HGNC id 24788
Location 2q11.2      Physical location : 100.889.753 - 100.939.195
Synonym symbol(s) RNF192
DNA
TYPE functioning gene
STRUCTURE 26.00 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepancreas exocrine   moderately
 stomach   moderately
Nervousbrain   highly
Reproductivefemale systemovary  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a RING-type zinc finger
  • mono polymer complex
    HOMOLOGY
    interspecies ortholog to murine Lonrf2
    Homologene
    FAMILY
    CATEGORY enzyme , signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
    text
  • extracellular region
  • basic FUNCTION
  • acting as a neurohypophyseal hormone
  • involved in ATP-dependent proteolysis
  • CELLULAR PROCESS protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • ubiquitin ligase complex
  • INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS