Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol LIX1L contributors: mct - updated : 19-12-2022
HGNC name limb and CNS expressed 1 like
HGNC id 28715
Location 1q21.1      Physical location : 145.477.084 - 145.499.090
Synonym name
  • Lix1 homolog (mouse) like
  • Synonym symbol(s) MGC46719, DKFZp762F237
    DNA
    TYPE functioning gene
    STRUCTURE 24.60 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 3991 - 337 - 2015 26310847
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • putative RNA-binding protein (RBP) containing a double-stranded RNA binding motif, which is highly expressed in various cancer tissues
  • plays an important role in post-transcriptional gene regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • unique link between DCHS1-based cell adhesions and the septin-actin cytoskeleton through interactions with LIX1L
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    digestiveliver 
    LIX1L represent potential therapeutic target for cholestatic liver diseases
    ANIMAL & CELL MODELS