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FLASH GENE
Symbol LIPN contributors: mct - updated : 18-08-2011
HGNC name lipase, family member N
HGNC id 23452
Corresponding disease
LMLI4 lamellar ichthyosis 4
Location 10q23.31      Physical location : 90.521.162 - 90.537.997
Synonym symbol(s) LI4, LIPL4, bA186O14.3
DNA
TYPE functioning gene
STRUCTURE 16.84 kb     9 Exon(s)
MAPPING cloned Y linked Y status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1197 - 398 - 2007 17562024
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Skin/Tegumentskin   highly Homo sapiens
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier liningepidermis highly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • involved in triglyceride metabolism
  • involvement of lipase N in the process of cornification
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by strongly induced during keratinocyte differentiation
    ASSOCIATED DISORDERS
    corresponding disease(s) LMLI4
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS