Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | LIPC | contributors: mct - updated : 26-03-2020 |
HGNC name | lipase, hepatic |
HGNC id | 6619 |
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Corresponding disease |
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Location | 15q21.3 Physical location : 58.724.174 - 58.861.072 | ||||
Synonym name | |||||
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Synonym symbol(s) | HL, HTGL, LIPH, HDLCQ12 | ||||
EC.number | 3.1.1.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 136.90 kb 9 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Binding site silencer cAMP HRE |
text structure | glucocorticoide-like responsive element, NRE (negative regulatory element) |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D15S150 - D15S1033 - LIPC LIPC - D15S148 - D15S964 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
isoforms | Precursor |
HOMOLOGY |
interspecies | ortholog to Lipc, Mus musculus |
homolog to Lipc, Rattus norvegicus | |
ortholog to lipc, Danio rerio |
Homologene |
FAMILY | |
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CATEGORY | enzyme |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | plasma lipid transport |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | other, |
protein | ![]() |
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cell & other |
REGULATION |
activated by | heparin |
induced by | thyroid hormones (T3) |
ASSOCIATED DISORDERS |
corresponding disease(s) | LIPCD , WHAR2 |
Susceptibility |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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