basic FUNCTION
| acting potentially as a dominant negative soluble receptor that would suppress the function of other LIR molecules |
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LILRA3 may likely play a role in chronic inflammatory conditions such as rheumatoid arthritis |
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LILRA3 is a potential new anti-inflammatory protein, and optimal glycosylation is required for its functions |
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beneficial role for LILRA3 in virus infections, especially in ssRNA viruses, like HIV, that engage TLR8 |
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LILRA3 may have a significant role in the immune pathogenesis of Severe aplastic anemia (SAA) |
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it may act as a significant function in the pathogenesis of autoimmune disorders |